Demographic and clinical features of 2 groups (with frequent or infrequent seizures) of patients with HWE
| Clinical Feature | Frequent-Seizure Group (>2/mo) | Infrequent-Seizure Group (≤2/mo) | P Value |
|---|---|---|---|
| Male/female ratio, n | 14:4 | 13:5 | .700 |
| Mean (±SD) age at evaluation, y | 29.06 ± 9.86 | 28.67 ± 10.78 | .910 |
| Mean (±SD) age at onset, y | 22.61 ± 8.39 | 20.69 ± 10.36 | .546 |
| Mean (±SD) duration of illness, y | 6.56 ± 6.48 | 7.39 ± 9.76 | .546 |
| HWE attacks per month | <.0001 | ||
| Mean (±SD) | 2.61 ± 0.69 | 0.62 ± 0.52 | |
| Median (range) | 2.5 (2–4) | 0.43 (0.02–1.66) | <.0001 |
| 1:1 episodes, n (%)a | 8 (44.4) | 1 (5.6) | .717 |
| Family history of any type of epilepsy, n (%) | 6 (33) | 5 (27) | .463 |
| History of febrile convulsion, n | 1 | 0 | |
| Family history of HWE, n (%) | 4 (22) | 1 (5.6) | |
| Self-induction phenomena, n (%) | 2 (11.1) | 2 (11.1) | |
| Abnormal EEG, n | 0 | 2 (11.1) | |
| Focal abnormalities in EEG, n | 0 | 2 | |
| Mean (±SD) time between last seizure and fMRI, days | 10.6 ± 7.5 | 9.38 ± 6.9 | .735 |
| Complex partial seizures, n | 12 | 10 | |
| Generalized tonic-clonic seizures, n | 6 | 8 |
↵a Patients who were having seizures every time they took a hot-water bath.