Univariate analysis comparing patients with moderate hypoperfusion (HIR ≤ 0.447) with patients with severe hypoperfusion (HIR > 0.447)a
| Low HIR (≤0.447) | High HIR (>0.447) | P Value | |
|---|---|---|---|
| No. | 31 | 31 | |
| Age (yr) (mean) (SD) | 67.5 (13.2) | 75.4 (13.7) | .02 |
| Female (%) (No.) | 51.6 (16) | 45.2 (14) | .8 |
| Arterial hypertension (%) (No.) | 80.6 (25) | 87.1 (27) | .73 |
| Diabetes mellitus (%) (No.) | 16.1 (5) | 25.8 (8) | .53 |
| Smoking (%) (No.) | 38.7 (12) | 9.7 (3) | .02 |
| Hypolipoproteinemia (%) (No.) | 54.8 (17) | 46.4 (15) | .9 |
| Atrial fibrillation (%) (No.) | 35.5 (11) | 45.2 (14) | .6 |
| No. of sections with FHV (median) (IQR) | 3 (1–7) | 7 (4–10) | <.01 |
| NIHSS score on admission (median) (IQR) | 5 (4–13) | 15 (11–18) | <.001 |
| Baseline lesion volume (mL) (median) (IQR) | 1.5 (0.27–5.8) | 6.7 (2.3–28.2) | <.01 |
| Infarct growth (median) (IQR) | 1.6 (0.2–10.6) | 6.2 (1.4–39.0) | <.01 |
| Baseline perfusion deficit (mL) (median) (IQR) | 41.2 (15.8–101.7) | 117.1 (56.0–171.6) | <.01 |
| Tmax ≥ 2 sec | 75.6 (24.7–179.4) | 143.1 (70.5–170.2) | .08 |
| Tmax ≥ 8 sec | 10.5 (3.7–61.9) | 88.2 (43.7–122.6) | <.001 |
| Vessel-occlusion size: | .47 | ||
| Large (%) (No.) | 19.4 (6) | 9.7 (3) | |
| Medium (%) (No.) | 80.6 (25) | 90.3 (28) | |
| Small (%) (No.) | 0 (0) | 0 (0) | |
| Recanalization (%) (No.) | 70 (21) | 58.1 (18) | .43 |
| Favorable outcome at 3 months (%) (No.) | 75.9 (22) | 32.3 (10) | <.01 |
↵a A Fisher exact test and Mann-Whitney U test were used for categoric and continuous variables, respectively.