Table 3:

Sensitivity and specificity for the presence of SWI-filtered phase, T2, and their overlapping white matter signal abnormalities among patients with clinically isolated syndrome, other neurologic disorders, and age- and sex-matched healthy controls^{^a}

	CIS vs HC			CIS vs OND
	Sensitivity	Specificity	Accuracy	Sensitivity	Specificity	Accuracy
Phase WM-SA
Total	70.8	76.6	73.7^{^b}	70.8	76.7	73.1^{^b}
Periventricular	66.7	76.6	71.6^{^b}	66.7	80	71.8^{^b}
Juxtacortical	27.1	100	63.2^{^b}	27.1	90	51.3
Infratentorial	0	100	–	0	100	–
Deep WM	27.1	93.8	60^{^c}	27.1	86.7	50
T2 WM-SA
Total	93.9	68.8	81.4^{^b}	95.8	13.3	64.1
Periventricular	93.8	91.5	92.6^{^b}	93.8	13.3	62.8
Juxtacortical	52.1	93.6	72.6^{^b}	52.1	83.3	64.1^{^c}
Infratentorial	18.8	100	58.9^{^c}	18.8	96.7	48.7
Deep WM	81.3	74.5	77.9^{^b}	81.3	53.3	70.5
Overlapping
Total	55.1	100	77.3b	56.3	90	69.2^{^b}
Periventricular	54.2	100	76.8^{^b}	54.2	90	67.9^{^b}
Juxtacortical	8.3	100	53.7^{^b}	8.3	93.3	41
Infratentorial	0	100	–	0	100	–
Deep WM	18.8	100	59^{^c}	18.8	93.3	47.4

Note:— indicates not applicable.
↵a Sensitivity and specificity were computed using cross-tabulations.
↵b P < .001.
↵c P < .01. P values have been corrected for false discovery rate at the P < .05 level.