Comparison of CBF in patients with NF-1 and control subjects by anatomic location and vascular territories
| Structure | Control CBF, mL/100 mg per minute (n = 14) | NF-1 CBF, mL/100 mg per minute (n = 14) | Mann-Whitney P Value |
|---|---|---|---|
| ACA territory | |||
| Anterior cingulate gyrus | 71 ± 7 | 61 ± 8 | a.001 |
| Medial frontal cortex | 65 ± 7 | 56 ± 9 | a.004 |
| Anterior caudate nucleus | 57 ± 9 | 51 ± 4 | .013 |
| ACA-MCA borderzone | |||
| Centrum semiovale | 28 ± 5 | 22 ± 4 | a.004 |
| MCA territory | |||
| Frontal operculum | 68 ± 8 | 60 ± 8 | .013 |
| Globus pallidus | 50 ± 6 | 44 ± 6 | .012 |
| MCA-PCA borderzone | |||
| Parietal cortex | 65 ± 9 | 55 ± 9 | .008 |
| Superomedial temporal cortex | 67 ± 9 | 60 ± 8 | .012 |
| Temporo-occipital cortex | 64 ± 10 | 51 ± 8 | a.002 |
| Anterior choroidal–PcomA–PCA | |||
| Thalamus | 55 ± 10 | 44 ± 8 | a.001 |
| PCA territory | |||
| Posterior cingulate gyrus | 70 ± 13 | 57 ± 8 | a.002 |
| Occipital cortex | 61 ± 13 | 45 ± 10 | a.001 |
Note:—ACA indicates anterior cerebral artery; PCA, posterior cerebral artery; PcomA, posterior communicating artery.
↵a Significant at ≤.004.