Table 1:

Characteristics of included studies

AuthorsStudy DesignSA TypePatients (levels)Preoperative PainPostoperative VASaLevel of Evidence
Age of FractureVAS
Alvarez et al1Prospective, double cohortVP101 (152)5 Months8.94.02
Conservative27 (28)5.8 Months7.37.3
Chen et al19RetrospectiveVP70 (87)8 Months80 (0–100)38 (0–100)4
Diamond et al20Prospective, non-randomizedVP88 (133)1–6 Weeks20 (0–25)8 (0–25)2
Conservative38 (NA)1–6 Weeks20 (0–25)19 (0–25)
Garfin et al21Prospective single-arm interventional cohortKP155 (214)128.5 Days15 (0–20)5 (0–20)4
Kallmes et al28Randomized double-blinded controlled trialPlacebo63 (93)20 Weeks7.23.91
VP68 (95)16 Weeks6.94.2
Kobayashi et al29ProspectiveVP175 (250)19 Days7.22.14
Lee et al30RetrospectiveKP105 (132)4.5 Weeks8.72.34
Liu et al31Randomized clinical trialKP50 (50)15.8 Days8.02.62
VP50 (50)17 Days7.92.3
Prather et al32ProspectiveVP50 (103)14 Months7.83.14
Rapan et al33NAVP55 (85)44 Days8.362.234
Rhyne et al25RetrospectiveKP52 (82)31 Weeks9.162.94
Rolloinghoff et al34ProspectiveKP45 (53)3 Weeks8.63.42
VP45 (51)3 Weeks8.84.8
Rousing et al35Randomized clinical trialConservative24 (32)6.7 Days8.8NA2
VP25 (31)8.4 Days7.52.0
Schofer et al36ProspectiveKP30 (30)9.5 Days8.23.22
VP30 (30)10.5 Days8.33.0
Vogl et al26RetrospectiveVP61 (NA)19 Days8.82.64
Voormolen et al9ProspectiveVP112 (168)4 Months8.83.34
Wardlaw et al31Randomized clinical trialConservative151 (195)6.4 Weeks7.05.92
KP149 (214)5.6 Weeks6.93.6
  • a Visual Analog Scale.