Serial apparent diffusion coefficient and single voxel proton MR spectroscopy values in two large hemispheric lesions
| No. of Days after Symptom Onset | ADC | NAA* | Creatine* | Choline* | Lactate | Lesion/Voxel† |
|---|---|---|---|---|---|---|
| Lesion 1 | ||||||
| 1 | 66.8 | 58.9 | 95.3 | 109.5 | 20.8 | 81 |
| 10 | 90.0 | 45.8 | 85.0 | 157.6 | 46.8 | 87 |
| 20 | 111.0 | 27.9 | 93.3 | 132.5 | 42.8 | 92 |
| 90 | 132.0 | 38.4 | 106.6 | 144.5 | 0.0 | 85 |
| Lesion 2 | ||||||
| 1 | 77.3 | 64.7 | 84.7 | 103.2 | 36.2 | 85 |
| 10 | 80.2 | 52.8 | 105.1 | 135.2 | 13.5 | 89 |
| 20 | 154 | 45.7 | 101.2 | 145.7 | 0.0 | 91 |
| 90 | 138 | 60.4 | 110.3 | 146.4 | 0.0 | 82 |
Note—ADC indicates apparent diffusion coefficient; NAA, N-acetylaspartate; rADC, ADC of lesion × 100/ADC of normal appearing white matter.
↵* Single voxel proton MR spectroscopy values expressed as a percentage calculated from the lesions in each time point, using the mean values obtained from the contralateral hemispheric normal appearing white matter as a reference.
↵† Percentage of lesion volume within the proton MR spectroscopy voxel.