Results from volume measurementsa
| Controls for HD Gene Carriers (n = 14) | HD Gene Carriers (n = 15) | P Value | Controls for HD Patients (n = 11) | HD Patients (n = 9) | P Value | |
|---|---|---|---|---|---|---|
| Caudate/TIV | 0.545 ± 0.099 | 0.452 ± 0.052 | .004 | 0.494 ± 0.076 | 0.264 ± 0.074 | <.001 |
| 0.559 (0.346–0.744) | 0.451 (0.348–0.556) | .01 | 0.472 (0.342–0.645) | 0.251 (0.115–0.412) | <.001 | |
| Putamen/TIV | 0.548 ± 0.058 | 0.464 ± 0.073 | .002 | 0.477 ± 0.076 | 0.248 ± 0.089 | <.001 |
| 0.535 (0.432–0.664) | 0.468 (0.317–0.611) | .002 | 0.484 (0.324–0.630) | 0.234 (0.069–0.427) | <.001 |
a Values are expressed as SD (upper row) and median (range, lower row); significance values are for the t test (upper row) and Mann-Whitney U test (lower row).