Table 2:

Histologic evaluations of mild HI-induced WM damage in injury and control ECs from D1 to D90 post-HI*

	Injury EC	Control EC	Ratio	P
LFB staining intensity (optical density)
D1	0.055 ± 0.006^a	0.081 ± 0.008^a	0.684 ± 0.086^a	<.01
D7	0.098 ± 0.008^b	0.129 ± 0.017^b	0.768 ± 0.097^b	<.01
D14	0.113 ± 0.014^c	0.143 ± 0.015^b	0.801 ± 0.160^b	<.01
D30	0.143 ± 0.015^d	0.173 ± 0.012^c	0.818 ± 0.083^b	<.01
D90	0.177 ± 0.021^e	0.214 ± 0.026^d	0.824 ± 0.092^b	<.01
Axon count
D1	201 ± 29^a	234 ± 32^a	0.859 ± 0.129	.074
D7	463 ± 48^a	503 ± 85^a	0.920 ± 0.084	.254
D14	679 ± 19	697 ± 32^a	0.974 ± 0.025	.087
D30	701 ± 132	716 ± 89^a	0.979 ± 0.084	.724
D90	1059 ± 476^b	1240 ± 402^b	0.854 ± 0.025	.335

Note:—WM indicates white matter; LFB, Luxol fast blue.
* A paired t test was used to evaluate the statistical significance between injury and control ECs. One-way analysis of variance followed by a Tukey test was used to evaluate the statistical significance among longitudinal time points. Superscript a,b,c,d,e reflect significant differences between time points. Values in the same column without a common superscript indicate a significant difference less than 0.05 between 2 time points. Values are shown as mean ± SD.