Diagnostic accuracies of Cho/Cr and/or LL/Cr ratios at short echo time (TE), intermediate TE, and both TEs in differentiation between low-grade (II) and high-grade (III + IV) gliomas using the cutoff (threshold) values obtained with minimum C1 error
Accuracy (%) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
---|---|---|---|---|---|
Grading with Cho/Cr and/or LL/Cr at short TE | 85.7 | 92.9 | 57.1 | 89.7 | 66.7 |
Grading with Cho/Cr and/or LL/Cr at intermediate TE | 82.9 | 89.3 | 57.1 | 89.3 | 57.1 |
Grading with Cho/Cr and/or LL/Cr at both TEs | 85.7 | 96.4 | 42.9 | 87.1 | 75.0 |
Note:—Cho indicates choline, Cr, creatine; NAA, N-acetylaspartate; LL, lipid and lactate; mIns, myo-inositol; PPV, positive predictive value; NPV, negative predictive value.