Patients with pathologic MR imaging in acute nonalcoholic Wernicke’s encephalopathy
| Patient No./Sex/Age (y) | Duration* (d) | Conscious State† | Duration of Thiamine Therapy and Follow-ups | Initial MR Imaging |
|---|---|---|---|---|
| 1/M/56 | 7 | Deep coma | 15 d (died) | T2W and FLAIR increased signals symmetrically in periaqueductal area, floor of fourth ventricle, periventricle region of third ventricle, medial thalami, capita of caudate nuclei, and frontal and parietal cortices |
| 2/M/27 | 5 | Mild coma | 2 y | T2W and FLAIR increased signals symmetrically in periaqueductal area, floor of fourth ventricle, periventricle region of third ventricle, medial thalami, and capita of caudate nuclei (Fig 4) |
| 3/F/47 | 10 | Deep coma | 2 y | T2W and FLAIR increased signals symmetrically in periaqueductal area, floor of fourth ventricle, periventricle region of third ventricle, medial thalami, capita of caudate nuclei, frontal and parietal cortices (Fig 3) |
| 4/M/16 | 3 | Drowsiness | 1 y | T2W and FLAIR increased signals in periaqueductal area |
| 5/F/19 | 5 | Drowsiness | 1 y | T2W and FLAIR increased signals in periaqueductal area (Fig 1) |
| 6/F/26 | 5 | Mild coma | 1 y | T2W and FLAIR increased signals symmetrically in periaqueductal area, floor of fourth ventricle, periventricle region of third ventricle, medial thalami, and capita of caudate nuclei (Fig 2) |
Note.—FLAIR indicates fluid-attenuated inversion recovery.
* From initial neurologic presentation to initial MR imaging.
† At initial MR imaging.