Table 3:

Diagnostic performance of imaging and clinical features for predicting the MSA with the predominant cerebellar ataxia group

ParametersSensitivityaSpecificityaF1 ScoreAUCbP Valuec
ICP0.69 [31/45]0.95 [20/21]0.730.82 (0.74–0.90)
MCP0.87 [39/45]0.48 [10/21]0.690.67 (0.55–0.79).029
HCB0.69 [31/45]0.71 [15/21]0.640.70 (0.58,0.82).052
ICP + MCP0.62 [28/45]0.95 [20/21]0.700.86 (0.78–0.98).114
Integrated modeld0.87 [39/45]1.00 [21/21]0.880.98 (0.96–1.00)<.001
  • Note:—The en dash indicates not applicable.

  • a Data in brackets indicate the number of corresponding patients for each of the metric.

  • b Data in parentheses are 95% CIs with the DeLong test.

  • c P values of AUCs compared with ICP as a reference.

  • d Integrated model includes the ICP, MCP sign, age, and disease duration as variables.