Diagnostic performance of imaging and clinical features for predicting the MSA with the predominant cerebellar ataxia group
Parameters | Sensitivitya | Specificitya | F1 Score | AUCb | P Valuec |
---|---|---|---|---|---|
ICP | 0.69 [31/45] | 0.95 [20/21] | 0.73 | 0.82 (0.74–0.90) | – |
MCP | 0.87 [39/45] | 0.48 [10/21] | 0.69 | 0.67 (0.55–0.79) | .029 |
HCB | 0.69 [31/45] | 0.71 [15/21] | 0.64 | 0.70 (0.58,0.82) | .052 |
ICP + MCP | 0.62 [28/45] | 0.95 [20/21] | 0.70 | 0.86 (0.78–0.98) | .114 |
Integrated modeld | 0.87 [39/45] | 1.00 [21/21] | 0.88 | 0.98 (0.96–1.00) | <.001 |
Note:—The en dash indicates not applicable.
↵a Data in brackets indicate the number of corresponding patients for each of the metric.
↵b Data in parentheses are 95% CIs with the DeLong test.
↵c P values of AUCs compared with ICP as a reference.
↵d Integrated model includes the ICP, MCP sign, age, and disease duration as variables.