Patient demographics and imaging characteristics
| Characteristic | CVF+ (n = 40) | CVF– (n = 32) |
|---|---|---|
| Mean age (range) (yr) | 61.6 (SD, 9.2) (34–83) | 58.2 (SD, 9.6) (22–71) |
| Sex female (%)/male (%) | 23 (58%)/17 (42%) | 23 (72%)/9 (28%) |
| Bern score | ||
| Median (range; IQR) | 6 (1–9; 3)a | 1 (0–6; 2) |
| Low probability 0–2 (%) | 1 (2.5%) | 28 (87.5%) |
| Intermediate probability 3–4 (%) | 10 (25%) | 3 (9.4%) |
| High probability 5–9 (%) | 29 (72.5%) | 1 (3.1%) |
| WMH | ||
| Mean total WMH (SD) | 7.9 (8.2)a | 20.7 (21.8) |
| Mean frontal WMH (SD) | 5.4 (6.5)a | 14.6 (14.1) |
| Median percentage frontal WMH (IQR) | 53.3 (52.2) | 70.6 (31.2) |
| WMH pattern (No.) (%) | ||
| Minimal | 22 (55%) | 10 (32.3%) |
| Migrainous | 5 (12.5%) | 15 (46.9%) |
| Microangiopathic | 13 (32.5%) | 7 (21.9%) |
Note:—IQR indicates interquartile range.
↵a Denotes P < .05 after Bonferroni adjustment. Patients with myelographically-proved CVF have higher Bern scores and fewer WMH. There is a strong correlation between the Bern score and CVF positivity (rpb = −0.82).