Table 2:

Imaging findings among those with secondary versus genetic/unknown cause of schizencephaly

Secondary (n = 14)Genetic/Unknown (n = 8)
Frontal12/14 (85.7)1/8 (12.5)
Parietal9/14 (64.3)1/8 (12.5)
Temporal6/14 (42.9)3/8 (37.5)
Occipital5/14 (35.7)6/8 (75)
Single defect5/14 (35.7)3/8 (37.5)
Open defect2/13 (15.4)a3/8 (37.5)
Abnormal CC3/12 (25)b7/8 (87.5)
Abnormal DGN8/13 (61.5)c0/8
Abnormal brainstem4/14 (28.6)3/8 (37.5)
Abnormal cerebellum4/14 (28.6)2/8 (25)
Abnormal vermis6/14 (42.9)4/8 (50)
Ventriculomegaly10/14 (71.4)7/8 (87.5)
Cortical malformation6/14 (42.9)7/8 (87.5)
Size (median) (IQR) (mm)b20 (9.5–33)6 (4–14)
  • a Both open and closed defect in 1 fetus.

  • b Could not be assessed in 2 fetuses.

  • c Could not be assessed in 1 fetus.