Updated classification criteria for GCA diagnosis
Classification Criteria for Giant Cell Arteritisa |
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2022 American College of Rheumatology & European Alliance of Associations for Rheumatology |
Absolute requirement |
• Age ≥50 years at time of diagnosis |
Additional clinical criteria |
• Morning stiffness in shoulder/neck area +2 |
• Sudden visual loss +3 |
• Jaw or tongue claudication +2 |
• New temporal headache +2 |
• Scalp tenderness +2 |
• Abnormal examination of temporal artery +2 |
Laboratory, imaging & biopsy criteria |
• Maximum ESR ≥50 mm/h or maximum CRP ≥10 mg/L +3 |
• Positive temporal artery biopsy or halo sign on ultrasound +5 |
• Bilateral axillary involvement +2 |
• FDG-PET activity throughout aorta +2 |
Sum the scores for 10 items, if present. A score of ≥6 points is needed for diagnosis of giant cell arteritis |
aConsideration while applying the criteria |
• Classification criteria should be applied when a diagnosis of medium-vessel or large-vessel vasculitis has been made |
• Alternate diagnosis mimicking vasculitis should be excluded before applying the criteria |
↵a Adapted from Ponte C, Grayson PC, Robson JC; DCVAS Study Group, et al. 2022 American College of Rheumatology/EULAR classification criteria for giant cell arteritis. Arthritis Rheumatol 2022;74:1881–89.