Updated classification criteria for GCA diagnosis

Classification Criteria for Giant Cell Arteritisa
2022 American College of Rheumatology & European Alliance of Associations for Rheumatology
Absolute requirement
 • Age ≥50 years at time of diagnosis
Additional clinical criteria
 • Morning stiffness in shoulder/neck area +2
 • Sudden visual loss +3
 • Jaw or tongue claudication +2
 • New temporal headache +2
 • Scalp tenderness +2
 • Abnormal examination of temporal artery +2
Laboratory, imaging & biopsy criteria
 • Maximum ESR ≥50 mm/h or maximum CRP ≥10 mg/L +3
 • Positive temporal artery biopsy or halo sign on ultrasound +5
 • Bilateral axillary involvement +2
 • FDG-PET activity throughout aorta +2
Sum the scores for 10 items, if present. A score of ≥6 points is needed for diagnosis of giant cell arteritis
aConsideration while applying the criteria
 • Classification criteria should be applied when a diagnosis of medium-vessel or large-vessel vasculitis has been made
 • Alternate diagnosis mimicking vasculitis should be excluded before applying the criteria
  • a Adapted from Ponte C, Grayson PC, Robson JC; DCVAS Study Group, et al. 2022 American College of Rheumatology/EULAR classification criteria for giant cell arteritis. Arthritis Rheumatol 2022;74:1881–89.