Comparison of the diffusion parameters within the nearby tracts connected to all lesions (PRLs and non-PRLs) versus within the lesions themselvesa
| Metrics | Tracts | Within-Lesion | Cohen d | P Value | q-Value |
|---|---|---|---|---|---|
| FA, mean ± SD | 0.383 ± 0.054 | 0.296 ± 0.052 | 1.38 | <.001 | 0.001 |
| QA, mean ± SD | 0.326 ± 0.062 | 0.290 ± 0.058 | 0.76 | <.001 | 0.001 |
| MD, mean ± SD | 1.092 ± 0.147 | 1.232 ± 0.218 | −0.70 | <.001 | 0.001 |
| AD, mean ± SD | 1.539 ± 0.184 | 1.572 ± 0.206 | −0.24 | .02 | 0.02 |
| RD, mean ± SD | 0.869 ± 0.140 | 1.018 ± 0.195 | −0.89 | <.001 | 0.001 |
| Iso, mean ± SD | 0.789 ± 0.226 | 0.836 ± 0.255 | −0.77 | <.001 | 0.001 |
| RDI, mean ± SD | 0.519 ± 0.094 | 0.535 ± 0.111 | −0.41 | <.001 | 0.001 |
↵a Paired t-tests and effect sizes were calculated within subjects who had at least 1 PRL (n = 49), P < .05 considered statistically significant. q-value represents the Benjamini-Hochberg FDR corrected P value at the table level.