Table 3:

Comparison of diffusion parameters between PRLs versus non-PRLs, within the lesionsa

MetricsPRLsNon-PRLsCohen dP Valueq-Value
Total LV,b mean ± SD, mL0.459 ± 1.258.33 ± 11.03–<.0010.008
FA, mean ± SD0.279 ± 0.0470.302 ± 0.056−0.30.040.16
QA, mean ± SD0.283 ± 0.0670.219 ± 0.056−0.13.380.43
MD, mean ± SD1.232 ± 0.2181.186 ± 0.1120.16.260.35
AD, mean ± SD1.581 ± 0.2651.560 ± 0.1350.07.630.63
RD, mean ± SD1.058 ± 0.2000.999 ± 0.1150.20.150.26
Iso, mean ± SD0.855 ± 0.2570.818 ± 0.2200.28.090.24
RDI, mean ± SD0.542 ± 0.1120.529 ± 0.0860.22.160.26

  • ↵a Paired t-test was calculated within subjects who had at least 1 PRL (n = 49), P < .05 considered statistically significant. q-value represents the Benjamini-Hochberg FDR corrected P value at the table level.

  • ↵b Non-PRL T2 LVs after excluding non-PRL T2 lesions overlapping or confluent with PRLs.