Patient characteristics of the entire cohort as stratified according to HIR statusa
| All Patients | HIR < 0.54 | HIR ≥ 0.54 | ||
|---|---|---|---|---|
| (n = 231) | (n = 183) | (n = 48) | P Value | |
| Characteristics | ||||
| Age (yr) | 70 (58–78) | 70 (59–79) | 67 (56–75) | .323 |
| Sex, female | 119 (51.5) | 96 (52.5) | 23 (47.9) | .628 |
| LKW to presentation 0–6 hr | 141 (61) | 111 (60.7) | 30 (62.6) | .869 |
| Initial NIHSS score | 11 (5–18) | 9 (4–16) | 17 (11–21.5) | <.001 |
| NIHSS score at 24 hr post-MT | 8 (2–14) | 6 (2–13) | 13 (7.5–20) | <.001 |
| Presence of END | 26 (11.3) | 20 (10.9) | 6 (12.5) | .798 |
| Use of rtPA | 76 (32.9) | 62 (33.9) | 14 (29.2) | .607 |
| ASPECTS | 9 (8–10) | 9 (8–10) | 8 (7–9) | .009 |
| Occlusion location | <.001 | |||
| LVO | 125 (54.1) | 88 (48.1) | 37 (77.1) | |
| DMVO | 106 (45.9) | 95 (51.9) | 11 (22.9) | |
| LA grade 3–4 | 50 (21.6) | 42 (23) | 8 (16.7) | .433 |
| Poor collateral grade (0–1) | 86 (37.2) | 52 (28.4) | 34 (70.8) | <.001 |
| Core volume (rCBF <30%, mL) | 8 (0–23.5) | 5 (0–13) | 53 (22–76) | <.001 |
| rCBF <38% (mL) | 17 (6–40) | 12 (5–24) | 76 (44–106.5) | <.001 |
| Tmax > 6 sec (mL) | 87 (50–137.5) | 71 (45.5–113) | 147.5 (97.5–209.5) | <.001 |
| Tmax > 10 sec (mL) | 25 (9.5–53) | 18 (6–35.5) | 91.5 (62.5–131.5) | <.001 |
| Mismatch volume (mL) | 64 (40–112.5) | 60 (39.5–102) | 89.5 (46–122.5) | .048 |
| Pre-MT SBP (mm Hg) | 151.5 (137–170) | 151 (135–170.5) | 152 (141–163) | .802 |
| TICI score | 1.000 | |||
| TICI 0–2a | 24 (10.4) | 19 (10.4) | 5 (10.4) | |
| TICI 2b–3 | 207 (89.6) | 164 (89.6) | 43 (89.6) | |
| No. of passes | 1 (1–2) | 1 (1–2) | 2 (1–3.5) | .030 |
| Stroke etiology | .153 | |||
| LAA | 28 (12.1) | 20 (10.9) | 8 (16.7) | |
| Cardioembolic | 96 (41.6) | 74 (40.4) | 22 (45.8) | |
| Cryptogenic | 103 (44.6) | 87 (47.5) | 16 (33.3) | |
| Other determined | 4 (1.7) | 2 (1.1) | 2 (4.2) |
Note:—LAA indicates large artery atherosclerosis.
↵a Data are No. (%) or median (25th–75th quartile).