PT  - JOURNAL ARTICLE
AU  - Shahrouki, P.
AU  - Gupta, R.
AU  - Belani, P.
AU  - Chien, A.
AU  - Doshi, A.H.
AU  - De Leacy, R.
AU  - Fifi, J.T.
AU  - Mocco, J.
AU  - Nael, K.
TI  - Differential Subsampling with Cartesian Ordering–MRA for Classifying Residual Treated Aneurysms
AID  - 10.3174/ajnr.A7532
DP  - 2022 Jun 01
TA  - American Journal of Neuroradiology
PG  - 887--892
VI  - 43
IP  - 6
4099  - http://www.ajnr.org/content/43/6/887.short
4100  - http://www.ajnr.org/content/43/6/887.full
SO  - Am. J. Neuroradiol.2022 Jun 01; 43
AB  - BACKGROUND AND PURPOSE: Differential Subsampling with Cartesian Ordering (DISCO), an ultrafast high-spatial-resolution head MRA, has been introduced. We aimed to determine the diagnostic performance of DISCO-MRA in grading residual aneurysm in comparison with TOF-MRA in patients with treated intracranial aneurysms.MATERIALS AND METHODS: Patients with endovascular treatment and having undergone DISCO-MRA, TOF-MRA, and DSA were included for review. The voxel size and acquisition time were 0.75 × 0.75 × 1 mm3/6 seconds for DISCO-MRA and 0.6 × 0.6 × 1 mm3/6 minutes for TOF-MRA. Residual aneurysms were determined using the Modified Raymond-Roy Classification on TOF-MRA and DISCO-MRA by 2 neuroradiologists independently and were compared against DSA as the reference standard. Statistical analysis was performed using the κ statistic and the χ2 test.RESULTS: Sixty-eight treated intracranial aneurysms were included. The intermodality agreement was κ = 0.82 (95% CI, 0.67–0.97) between DISCO and DSA and 0.44 (95% CI, 0.28–0.61) between TOF and DSA. Modified Raymond-Roy Classification scores matched DSA scores in 60/68 cases (88%; χ2 = 144.4, P < .001 for DISCO and 46/68 cases (68%; χ2 = 65.0, P < .001) for TOF. The diagnostic accuracy for the detection of aneurysm remnants was higher for DISCO (0.96; 95% CI, 0.88–0.99) than for TOF (0.79; 95% CI, 0.68–0.88).CONCLUSIONS: In patients with endovascularly treated intracranial aneurysms, DISCO-MRA provides superior diagnostic performance in comparison with TOF-MRA in delineating residual aneurysms in a fraction of the time.ARCAutocalibrating Reconstruction for CartesianCEcontrast-enhancedDISCODifferential Subsampling with Cartesian OrderingEVTendovascular treatmentIAintracranial aneurysmIQRinterquartile rangeMRRCModified Raymond-Roy ClassificationNPVnegative predictive valuePPVpositive predictive value