RT Journal Article SR Electronic T1 The hypoglossal canal: normal MR enhancement pattern. JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1707 OP 1710 VO 16 IS 8 A1 Voyvodic, F A1 Whyte, A A1 Slavotinek, J YR 1995 UL http://www.ajnr.org/content/16/8/1707.abstract AB PURPOSE To review the anatomy of the hypoglossal canal and present the normal precontrast and postcontrast MR appearance of axial posterior fossa images. METHODS Thirty-one axial MR examinations of the normal posterior fossa were retrospectively reviewed. RESULTS The hypoglossal canals are well seen on 3-mm-thick axial MR images of the posterior fossa (28 [90%] of 31 patients). Symmetric intense intracanalicular enhancement after intravenous administration of gadopentetate dimeglumine is routine, typically with minor anterior extension into the nasopharyngeal region (28 [100%] of 28). A linear filling defect traversing the enhanced canal often is seen (21 [75%] of 28) and may represent hypoglossal nerve rootlets. Circumferential enhancement of the meninges at the level of the foramen magnum was a common finding (19 [64%] of 28). CONCLUSION Enhancement within the hypoglossal canal with anterior extension beneath the skull base is a normal finding. This pattern is characteristic enough on MR imaging to aid interpretation of skull base lesions and to exclude the possibility of a mass within the hypoglossal canal.