RT Journal Article SR Electronic T1 MR Spectroscopy in Radiation Injury JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1469 OP 1476 DO 10.3174/ajnr.A1580 VO 30 IS 8 A1 Sundgren, P.C. YR 2009 UL http://www.ajnr.org/content/30/8/1469.abstract AB SUMMARY: Detecting a new area of contrast enhancement in or in the vicinity of a previously treated brain tumor always causes concern for both the patient and the physician. The question that immediately arises is whether this new lesion is recurrent tumor or a treatment effect. The differentiation of recurrent tumor or progressive tumor from radiation injury after radiation therapy is often a radiologic dilemma regardless the technique used, CT or MR imaging. The purpose of this article was to review the utility of one of the newer MR imaging techniques, MR spectroscopy, to distinguish recurrent tumor from radiation necrosis or radiation injury.