PT  - JOURNAL ARTICLE
AU  - D’Amore, F.
AU  - Vinacci, G.
AU  - Agosti, E.
AU  - Cariddi, L.P.
AU  - Terrana, A.V.
AU  - Vizzari, F.A.
AU  - Mauri, M.
AU  - Giorgianni, A.
TI  - Pressing Issues in COVID-19: Probable Cause to Seize SARS-CoV-2 for Its Preferential Involvement of Posterior Circulation Manifesting as Severe Posterior Reversible Encephalopathy Syndrome and Posterior Strokes
AID  - 10.3174/ajnr.A6679
DP  - 2020 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1800--1803
VI  - 41
IP  - 10
4099  - http://www.ajnr.org/content/41/10/1800.short
4100  - http://www.ajnr.org/content/41/10/1800.full
SO  - Am. J. Neuroradiol.2020 Oct 01; 41
AB  - SUMMARY: Since December 2019, a novel Severe Acute Respiratory Syndrome coronavirus 2 from China has rapidly spread worldwide. Although respiratory involvement is the mainstay of coronavirus disease 2019 (COVID-19), systemic involvement has recently drawn more attention. In particular, a number of recent articles have shed light on the nervous system as one of the possible targets. At our institution, we observed 15 patients with acute brain vascular manifestations; most interesting, we had a higher prevalence of the posterior circulation acute impairment. In our series, 7 patients had acute posterior cerebral injury: 1, hemorrhagic posterior reversible encephalopathy syndrome; 5, posterior circulation ischemic stroke; and 1, parieto-occipital hemorrhagic stroke. On the basis of our evidence and previous basic science reports, we believe a common etiopathogenetic thread may connect ischemic/hemorrhagic events of the posterior circulation and posterior reversible encephalopathy syndrome in the setting of COVID-19.COVID-19coronavirus disease 2019PRESposterior reversible encephalopathy syndromeSARS-CoV-2Severe Acute Respiratory Syndrome coronavirus 2