RT Journal Article SR Electronic T1 Correction of Motion Artifacts Using a Multiscale Fully Convolutional Neural Network JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 416 OP 423 DO 10.3174/ajnr.A6436 VO 41 IS 3 A1 Sommer, K. A1 Saalbach, A. A1 Brosch, T. A1 Hall, C. A1 Cross, N.M. A1 Andre, J.B. YR 2020 UL http://www.ajnr.org/content/41/3/416.abstract AB BACKGROUND AND PURPOSE: Motion artifacts are a frequent source of image degradation in the clinical application of MR imaging (MRI). Here we implement and validate an MRI motion-artifact correction method using a multiscale fully convolutional neural network.MATERIALS AND METHODS: The network was trained to identify motion artifacts in axial T2-weighted spin-echo images of the brain. Using an extensive data augmentation scheme and a motion artifact simulation pipeline, we created a synthetic training dataset of 93,600 images based on only 16 artifact-free clinical MRI cases. A blinded reader study using a unique test dataset of 28 additional clinical MRI cases with real patient motion was conducted to evaluate the performance of the network.RESULTS: Application of the network resulted in notably improved image quality without the loss of morphologic information. For synthetic test data, the average reduction in mean squared error was 41.84%. The blinded reader study on the real-world test data resulted in significant reduction in mean artifact scores across all cases (P < .03).CONCLUSIONS: Retrospective correction of motion artifacts using a multiscale fully convolutional network is promising and may mitigate the substantial motion-related problems in the clinical MRI workflow.FCNfully convolutional neural networkMSEmean squared errorSSIMstructural similarity index