PT  - JOURNAL ARTICLE
AU  - Rigotti, D.J.
AU  - Inglese, M.
AU  - Babb, J.S.
AU  - Rovaris, M.
AU  - Benedetti, B.
AU  - Filippi, M.
AU  - Grossman, R.I.
AU  - Gonen, O.
TI  - Serial Whole-Brain <em>N</em>-Acetylaspartate Concentration in Healthy Young Adults
AID  - 10.3174/ajnr.A0712
DP  - 2007 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1650--1651
VI  - 28
IP  - 9
4099  - http://www.ajnr.org/content/28/9/1650.short
4100  - http://www.ajnr.org/content/28/9/1650.full
SO  - Am. J. Neuroradiol.2007 Oct 01; 28
AB  - SUMMARY: Although the concentration of N-acetylaspartate (NAA) is often used as a neuronal integrity marker, its normal temporal variations are not well documented. To assess them over the 1–2 year periods of typical clinical trials, the whole-brain NAA concentration was measured longitudinally, over 4 years, in a cohort of healthy young adults. No significant change (adjusted for both sex and age) was measured either interpersonally or intrapersonally over the entire duration of the study.