PT - JOURNAL ARTICLE AU - Hong, J.-S. AU - Kao, Y.-H. AU - Chang, F.-C. AU - Lin, C.-J. TI - Validating the Automatic Independent Component Analysis of DSA AID - 10.3174/ajnr.A5963 DP - 2019 Jan 24 TA - American Journal of Neuroradiology 4099 - http://www.ajnr.org/content/early/2019/01/24/ajnr.A5963.short 4100 - http://www.ajnr.org/content/early/2019/01/24/ajnr.A5963.full AB - SUMMARY: Time-density curve analysis of DSA provides useful blood flow information. However, manually selecting the ROI is time-consuming. We developed an automatic technique to provide arterial, capillary, and venous vasculatures with corresponding time-density curves. This study retrospectively analyzed the data of 36 patients with unilateral carotid stenosis. We found that the full width at half maximum of the time-density curve for the automatically segmented capillary vasculature is a suitable representation of the cerebral circulation time.CCTcerebral circulation timeFWHMfull width at half maximumI1 and I2the internal carotid artery at 2 locationsIAcervical internal carotid artery in the lateral viewIBcavernous segment of the internal carotid artery in the lateral viewMCPmanually selected capillary phasePAposteroanteriorTDCtime-density curve