RT Journal Article
SR Electronic
T1 Vessel Wall MRI for Targeting Biopsies of Intracranial Vasculitis
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 2034
OP 2036
DO 10.3174/ajnr.A5801
VO 39
IS 11
A1 Zeiler, S.R.
A1 Qiao, Y.
A1 Pardo, C.A.
A1 Lim, M.
A1 Wasserman, B.A.
YR 2018
UL http://www.ajnr.org/content/39/11/2034.abstract
AB SUMMARY: Central nervous system vasculitides are elusive diseases that are challenging to diagnose because brain biopsies have high false-negative rates. We sought to test the ability of contrast-enhanced, high-resolution 3D vessel wall MR imaging to identify vascular inflammation and direct open biopsies of intracranial target vessels and adjacent brain parenchyma. Eight of 9 specimens revealed vascular inflammation. We conclude that vessel wall MR imaging can identify inflamed intracranial vessels, enabling precise localization of biopsy targets.CNSVCNS vasculitisVWMRIvessel wall MR imaging