PT - JOURNAL ARTICLE AU - Zeiler, S.R. AU - Qiao, Y. AU - Pardo, C.A. AU - Lim, M. AU - Wasserman, B.A. TI - Vessel Wall MRI for Targeting Biopsies of Intracranial Vasculitis AID - 10.3174/ajnr.A5801 DP - 2018 Nov 01 TA - American Journal of Neuroradiology PG - 2034--2036 VI - 39 IP - 11 4099 - http://www.ajnr.org/content/39/11/2034.short 4100 - http://www.ajnr.org/content/39/11/2034.full SO - Am. J. Neuroradiol.2018 Nov 01; 39 AB - SUMMARY: Central nervous system vasculitides are elusive diseases that are challenging to diagnose because brain biopsies have high false-negative rates. We sought to test the ability of contrast-enhanced, high-resolution 3D vessel wall MR imaging to identify vascular inflammation and direct open biopsies of intracranial target vessels and adjacent brain parenchyma. Eight of 9 specimens revealed vascular inflammation. We conclude that vessel wall MR imaging can identify inflamed intracranial vessels, enabling precise localization of biopsy targets.CNSVCNS vasculitisVWMRIvessel wall MR imaging