RT Journal Article
SR Electronic
T1 Diffusion-Weighted Zonal Oblique Multislice–EPI Enhances the Detection of Small Lesions with Diffusion Restriction in the Brain Stem and Hippocampus: A Clinical Report of Selected Cases
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1255
OP 1259
DO 10.3174/ajnr.A5635
VO 39
IS 7
A1 Sartoretti, T.
A1 Sartoretti, E.
A1 Binkert, C.
A1 Gutzeit, A.
A1 Reischauer, C.
A1 Czell, D.
A1 Wyss, M.
A1 Brüllmann, E.
A1 Sartoretti-Schefer, S.
YR 2018
UL http://www.ajnr.org/content/39/7/1255.abstract
AB SUMMARY: Diffusion restriction is the morphologic hallmark of acute ischemic infarcts and excitotoxic brain injury in various cerebral pathologies. Diffusion restriction is visible as hyperintensity on DWI and as hypointensity on ADC maps. Due to the vicinity of multiple anatomic structures in the brain stem and hippocampus, very small lesions with diffusion restriction may result in severe clinical symptomatology, but these small lesions easily go undetected on standard cerebral DWI due to insufficient spatial resolution, T2* blurring, and image artifacts caused by susceptibility-related image distortions. Diffusion-weighted zonal oblique multislice–EPI with reduced FOV acquisition permits a considerable increase in spatial resolution and enhances the visualization of very small pathologic lesions in the brain stem and hippocampus. Improved performance in the depiction of different pathologic lesions with diffusion restriction in the brain stem and hippocampus using this sequence compared with standard DWI in selected cases is presented.CN IIIoculomotor nerve nucleus areaCN VIabducens nerve nucleus areaDWdiffusion-weightedsshot SEsingle-shot spin-echoTGAtransient global amnesiaZOOMzonal oblique multislice