RT Journal Article SR Electronic T1 Physiologic intracranial calcification with hyperintensity on MR imaging: case report and experimental model. JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1145 OP 1148 VO 9 IS 6 A1 Dell, L A A1 Brown, M S A1 Orrison, W W A1 Eckel, C G A1 Matwiyoff, N A YR 1988 UL http://www.ajnr.org/content/9/6/1145.abstract AB CT and MR imaging showed basal ganglia calcification that appeared as high signal intensity on T1-weighted images of a patient with pseudohypoparathyroidism. MR imaging of an experimental model of calcium phosphate suspensions showed a signal similar to that seen in the patient. Additionally, T1 and T2 relaxation times of the solutions were measured and showed decreases in both parameters with increasing calcium phosphate concentrations. Intracranial calcification can appear as high signal intensity on T1-weighted images. An experimental model shows that the calcium salt decreases the T1 of surrounding water. Therefore, calcium, and possibly other elements, may induce paramagnetic susceptibility effects.