RT Journal Article
SR Electronic
T1 Diffuse Cortical Necrosis in a Neonate with Incontinentia Pigmenti and an Encephalitis-Like Presentation
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1580
OP 1582
VO 26
IS 6
A1 Wolf, Nicole I.
A1 Krämer, Nikola
A1 Harting, Inga
A1 Seitz, Angelika
A1 Ebinger, Friedrich
A1 Pöschl, Johannes
A1 Rating, Dietz
YR 2005
UL http://www.ajnr.org/content/26/6/1580.abstract
AB Summary: Incontinentia pigmenti is a rare neurocutaneous disorder that may present with neurologic symptoms, in addition to a characteristic vesicular rash within the first days of life. We describe a neonate girl presenting with a rash and an encephalopathy who was first thought to suffer from a viral infection and was only later recognized as being affected by incontinentia pigmenti. Cerebral MR imaging showed extensive cortical necrosis in the acute period. Incontinentia pigmenti should be included in the differential diagnosis of encephalopathy and cutaneous involvement in neonates, after a viral infection has been ruled out.