RT Journal Article
SR Electronic
T1 Digitized Cerebral Synchrotron Radiation Angiography: Quantitative Evaluation of the Canine Circle of Willis and Its Large and Small Branches
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 801
OP 806
VO 20
IS 5
A1 Tanaka, Etsuro
A1 Tanaka, Akira
A1 Sekka, Takafumi
A1 Shinozaki, Yoshiro
A1 Hyodo, Kazuyuki
A1 Umetani, Keiji
A1 Mori, Hidezo
YR 1999
UL http://www.ajnr.org/content/20/5/801.abstract
AB BACKGROUND AND PURPOSE: Conventional X-ray angiography lacks the sensitivity and spatial resolution needed to detect small amounts of iodinated contrast material and to quantitate diameters of the small vessels in the brain. The purpose of this study was to ascertain whether digitized synchrotron radiation microangiography, with the use of a high-definition TV camera system, can accurately show small cerebral vessels.METHODS: Six anesthetized dogs were exposed to monochromatic synchrotron radiation with an energy level of 33.3 keV optimized for iodine detection while iodinated contrast material was injected into the brachiocephalic and vertebral arteries. The images were detected with a high-definition TV camera system with a spatial resolution of 30 μm. In all, 26 cerebral angiograms of the circle of Willis with its branches were obtained, and the images were digitized at a workstation.RESULTS: The small branches of the circle of Willis were clearly visible on all images. Vasodilatation of the circle of Willis and its large and small branches induced by CO2 inhalation was quantitatively confirmed on the images: for example, the diameter of one small branch was increased from 0.24 ± 0.04 mm to 0.38 ± 0.12 mm. Temporal subtraction improved the image quality.CONCLUSION: The synchrotron radiation angiographic system is useful for visualizing large and small vessels deep in the brain as well as for quantitating their diameters.