PT  - JOURNAL ARTICLE
AU  - Nishimura, S.
AU  - Hirai, T.
AU  - Shigematsu, Y.
AU  - Kitajima, M.
AU  - Morioka, M.
AU  - Kai, Y.
AU  - Minoda, R.
AU  - Uetani, H.
AU  - Murakami, R.
AU  - Yamashita, Y.
TI  - Evaluation of Brain and Head and Neck Tumors with 4D Contrast-Enhanced MR Angiography at 3T
AID  - 10.3174/ajnr.A2819
DP  - 2012 Mar 01
TA  - American Journal of Neuroradiology
PG  - 445--448
VI  - 33
IP  - 3
4099  - http://www.ajnr.org/content/33/3/445.short
4100  - http://www.ajnr.org/content/33/3/445.full
SO  - Am. J. Neuroradiol.2012 Mar 01; 33
AB  - BACKGROUND AND PURPOSE: Systematic assessment of brain and head and neck tumors with 4D-CE-MRA at 3T has not been investigated. The purpose of this study was to test the hypothesis that 4D-CE-MRA at 3T can replace DSA in the identification of feeding arteries and tumor stain to plan interventional procedures in hypervascular brain and head and neck tumors. MATERIALS AND METHODS: Fifteen consecutive patients with brain and head and neck tumors underwent 4D-CE-MRA at 3T and DSA. 4D-CE-MRA combined randomly segmented central k-space ordering, keyhole imaging, SENSE, and half-Fourier imaging. We obtained 30 dynamic scans every 1.9 seconds at an acquired spatial resolution of 0.9 × 0.9 × 1.5 mm; the matrix was 256 × 256. Two independent observers inspected the 4D-CE-MRA images for the main arterial feeders and tumor stain. Interobserver and intermodality agreement was assessed by κ statistics. RESULTS: For 4D-CE-MRA, the interobserver agreement was fair with respect to the main arterial feeders and very good for the degree of tumor stain (κ = 0.28 and 0.87, respectively). Intermodality agreement was moderate for the main arterial feeders (κ = 0.45) and good for the tumor stain (κ = 0.74). CONCLUSIONS: Although 4D-CE-MRA may be useful for evaluating tumor stain in hypervascular brain and head and neck tumors, it is not able to replace DSA in planning interventional procedures. CE-MRAcontrast-enhanced MRACENTRAcontrast-enhanced robust-timing angiographyCIconfidence intervalSENSEsensitivity encoding