RT Journal Article SR Electronic T1 Comparison of Transcranial Color-Coded Duplex Sonography and Cranial CT Measurements for Determining Third Ventricle Midline Shift in Space-Occupying Stroke JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1567 OP 1571 VO 20 IS 8 A1 Stolz, Erwin A1 Gerriets, Tibo A1 Fiss, Ingo A1 Babacan, Sait S. A1 Seidel, Günter A1 Kaps, Manfred YR 1999 UL http://www.ajnr.org/content/20/8/1567.abstract AB BACKGROUND AND PURPOSE: Transcranial color-coded duplex sonography (TCCS) allows the noninvasive, easily reproducible measurement of midline dislocation (MLD) of the third ventricle in space-occupying stroke, even in critically ill patients. However, the method has been validated only in a small number of subjects. The aim of this study was to test the method under clinical conditions.METHODS: In 61 prospectively recruited patients (mean age, 62 ± 15 years) with supratentorial ischemic infarction or intracranial hemorrhage, the sonographic measurement of MLD was compared with cranial CT data in a 12-hour time window. Subgroup analysis was also undertaken for comparing TCCS and cranial CT measurements within a 3-hour time window.RESULTS: One hundred twenty-two data pairs of TCCS and cranial CT MLD measurements were correlated within the 12-hour time window. TCCS and cranial CT measurements of MLD correlated both in the total patient group and in the different subgroups with coefficients of over 0.9. The 2-SD confidence interval of the difference between the TCCS measurements and the respective means of both methods in the total patient collective was ±1.78 mm.CONCLUSION: TCCS provides a noninvasive, easily reproducible and reliable method for monitoring MLD of the third ventricle in stroke patients. It is particularly suitable for critically ill patients who are not fit for transportation.