PT - JOURNAL ARTICLE AU - Alfalahi, Afra AU - Omar, Abdelsimar Il AU - Fox, Krystal AU - Spears, Julian AU - Sharma, Malika AU - Bharatha, Aditya AU - Munoz, David G. AU - Suthiphosuwan, Suradech TI - Epstein-Barr Virus–Associated Smooth-Muscle Tumor of the Brain AID - 10.3174/ajnr.A8258 DP - 2024 Jul 01 TA - American Journal of Neuroradiology PG - 850--854 VI - 45 IP - 7 4099 - http://www.ajnr.org/content/45/7/850.short 4100 - http://www.ajnr.org/content/45/7/850.full SO - Am. J. Neuroradiol.2024 Jul 01; 45 AB - Epstein-Barr virus, a herpesvirus, has been associated with a variety of cancers, including Burkitt, Hodgkin, and non-Hodgkin lymphomas; posttransplant lymphoproliferative disorders; gastric carcinoma; and nasopharyngeal carcinoma, in both immunocompetent and immunocompromised individuals. Previous studies have established a connection between Epstein-Barr virus and the development of smooth-muscle tumors. Smooth-muscle tumors of the brain are very rare and are often misdiagnosed as meningiomas on imaging. To our knowledge, advanced imaging findings such as MR perfusion of smooth-muscle tumors of the brain have never been reported. We describe the radiologic and pathologic features of the Epstein-Barr virus–associated smooth-muscle tumors of the brain in a person with newly diagnosed advanced HIV.EBVEpstein-Barr virusEBV-SMTEpstein-Barr virus–associated smooth-muscle tumorrCBVrelative CBVSMTsmooth-muscle tumor