RT Journal Article
SR Electronic
T1 Expanding the Imaging Spectrum of Polymorphous Low-Grade Neuroepithelial Tumor of the Young in Children
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 483
OP 487
DO 10.3174/ajnr.A8145
VO 45
IS 4
A1 Cerron-Vela, Carmen
A1 Gonçalves, Fabricio Guimarães
A1 Viaene, Angela N.
A1 Tierradentro-García, Luis Octavio
A1 Vossough, Arastoo
YR 2024
UL http://www.ajnr.org/content/45/4/483.abstract
AB SUMMARY: Polymorphous low-grade neuroepithelial tumors of the young (PLNTY) are rare brain tumors first described in 2017 and recently included in the 2021 5th World Health Organization Classification of Tumors of the Central Nervous System. They typically affect children and young adults. Few pediatric cases have been reported in the literature. The most common imaging features described, include location within the temporal lobe, involvement of the cortical/subcortical region, coarse calcifications, and well-defined margins with solid and cystic morphology, with slight-or-no enhancement. However, there is limited information on imaging features in children. We present the imaging spectrum of neuroimaging features in a series of pediatric patients with a histologically and molecularly proved PLNTY diagnosis. Coarse calcifications are uncommon in children compared with the adult literature, and they may develop with time. The transmantle-like sign can be observed, and adjacent cortical dysplasia may be seen. Seizure recurrence may occur despite gross total resection of the tumor.DNETdysembryoplastic neuroepithelial tumorIQRinterquartile rangePLNTYpolymorphous low-grade neuroepithelial tumor of the youngTLStransmantle-like signWHO5World Health Organization Classification of Tumors of the Central Nervous System, 5th edition