RT Journal Article
SR Electronic
T1 Decreases of Blood Oxygenation Level—Dependent Signal in the Activated Motor Cortex during Functional Recovery after Resection of a Glioma
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1242
OP 1246
VO 25
IS 7
A1 Murata, Yoshihiro
A1 Sakatani, Kaoru
A1 Katayama, Yoichi
A1 Fujiwara, Norio
A1 Hoshino, Tatsuya
A1 Fukaya, Chikashi
A1 Yamamoto, Takamitsu
YR 2004
UL http://www.ajnr.org/content/25/7/1242.abstract
AB Summary: The present case demonstrates that the blood oxygenation level—dependent (BOLD) signal intensity can decrease in the activated motor cortex on the lesion side (left) of a patient with a left frontal glioma during functional recovery after surgery. Near-infrared spectroscopy revealed that the decrease of BOLD signal was associated with increases of cerebral blood volume and deoxyhemoglobin concentrations in the cerebral vessels. This implies that the interpretation of results obtained by functional MR imaging in patients with brain disorders must take into consideration such atypically evoked cerebral blood oxygenation changes, which do not increase the BOLD signals.