RT Journal Article
SR Electronic
T1 Increased Uptake of Technetium-99m-Hexamethylpropyleneamine Oxime Related to Primary Leptomeningeal Melanoma
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1404
OP 1406
VO 23
IS 8
A1 Sagiuchi, Takao
A1 Ishii, Katsumi
A1 Utsuki, Satoshi
A1 Asano, Yuuji
A1 Tsukahara, Shinya
A1 Kan, Shinichi
A1 Fujii, Kiyotaka
A1 Hayakawa, Kazushige
YR 2002
UL http://www.ajnr.org/content/23/8/1404.abstract
AB Summary: We present an autopsy case of primary leptomeningeal melanoma visualized with technetium-99m-hexamethylpropyleneamine oxime (Tc-99m-HMPAO) single photon emission CT (SPECT) of the brain. Increased uptake of Tc-99m-HMPAO coincided with leptomeningeal enhancement on MR images and with the tumor location of the autopsy findings. It was thought that Tc-99m-HMPAO could correlate closely with melanoma. Tc-99m-HMPAO SPECT clearly showed primary leptomeningeal melanoma and severe hypoperfusion induced by intracranial hypertension and tumor proliferation.