More articles from Head & Neck
- Imaging Appearance of SMARCB1 (INI1)-Deficient Sinonasal Carcinoma: A Newly Described Sinonasal Malignancy
SMARCB1 (INI1) is a tumor-suppressor gene that has been implicated in a growing number of malignancies involving multiple anatomic sites, including the kidneys, soft tissues, and the CNS (See OMIM *601607). The authors describe a case series of 17 patients collected from 6 different centers to give a comprehensive description of the appearance of these tumors on CT, MR, and PET/CT studies. SMARCB1 (INI1)-deficient sinonasal carcinoma should be included in the differential diagnosis of a central sinonasal mass demonstrating aggressive imaging features, particularly when there is associated calcification.
- Diagnostic Accuracy of Screening MR Imaging Using Unenhanced Axial CISS and Coronal T2WI for Detection of Small Internal Auditory Canal Lesions
T2-weighted and CISS images were compared with thin-section postcontrast T1 sequences for the detection of small (<10 mm) internal auditory canal schwannomas in 23 patients. The authors concluded that screening noncontrast MR imaging using a combination of axial CISS and coronal T2WI sequences can detect small internal auditory canal lesions with 100% sensitivity and excellent interobserver agreement.