Infarct Growth despite Successful Endovascular Reperfusion in Acute Ischemic Stroke: A Meta-analysis

References

1. 1.↵
   2. Yoo AJ,
   3. Chaudhry ZA,
   4. Nogueira RG, et al

   . Infarct volume is a pivotal biomarker after intra-arterial stroke therapy. Stroke 2012;43:1323–30 doi:10.1161/STROKEAHA.111.639401 pmid:22426317

   Abstract/FREE Full Text
2. 2.↵
   2. Zaidi SF,
   3. Aghaebrahim A,
   4. Urra X, et al

   . Final infarct volume is a stronger predictor of outcome than recanalization in patients with proximal middle cerebral artery occlusion treated with endovascular therapy. Stroke 2012;43:3238–44 doi:10.1161/STROKEAHA.112.671594 pmid:23160876

   Abstract/FREE Full Text
3. 3.↵
   2. Regenhardt RW,
   3. Etherton MR,
   4. Das AS, et al

   . White matter acute infarct volume after thrombectomy for anterior circulation large vessel occlusion stroke is associated with long term outcomes. J Stroke Cerebrovasc Dis 2021;30:105567 doi:10.1016/j.jstrokecerebrovasdis.2020.105567 pmid:33385939

   CrossRefPubMed
4. 4.↵
   2. De Meyer SF,
   3. Denorme F,
   4. Langhauser F, et al

   . Thromboinflammation in stroke brain damage. Stroke 2016;47:1165–72 doi:10.1161/STROKEAHA.115.011238 pmid:26786115

   FREE Full Text
5. 5.↵
   2. Desilles JP,
   3. Mazighi M,
   4. Ho-Tin-Noé B

   . Letter by Desilles regarding article, “Ischemia-Reperfusion Injury After Endovascular Thrombectomy for Ischemic Stroke.” Stroke 2019;50:e98 doi:10.1161/STROKEAHA.118.024391 pmid:30727828

   CrossRefPubMed
6. 6.↵
   2. Gauberti M,
   3. Lapergue B,
   4. Martinez de Lizarrondo S, et al

   . Ischemia-reperfusion injury after endovascular thrombectomy for ischemic stroke. Stroke 2018;49:3071–74 doi:10.1161/STROKEAHA.118.022015 pmid:30571423

   CrossRefPubMed
7. 7.↵
   2. Moher D,
   3. Liberati A,
   4. Tetzlaff J, et al

   . for the PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 2009;6:e1000097 doi:10.1371/journal.pmed.1000097 pmid:19621072

   CrossRefPubMed
8. 8.↵
   2. Luo D,
   3. Wan X,
   4. Liu J, et al

   . Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range. Stat Methods Med Res 2018;27:1785–1805 doi:10.1177/0962280216669183 pmid:27683581

   CrossRefPubMed
9. 9.↵
   2. Shi J,
   3. Luo D,
   4. Weng H, et al

   . Optimally estimating the sample standard deviation from the five-number summary. Res Synth Methods 2020;11:641–54 doi:10.1002/jrsm.1429 pmid:32562361

   CrossRefPubMed
10. 10.↵
    2. Sterne JA,
    3. Hernán MA,
    4. Reeves BC, et al

    . ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 2016;355:i4919 doi:10.1136/bmj.i4919 pmid:27733354

    FREE Full Text
11. 11.↵
    2. McGuinness LA,
    3. Higgins JP

    . Risk-of-bias VISualization (robvis): an R package and Shiny web app for visualizing risk-of-bias assessments. Res Synth Methods 2021;12:55–61 doi:10.1002/jrsm.1411 pmid:32336025

    CrossRefPubMed
12. 12.↵
    2. Andrapalliyal N,
    3. Handshoe Lacy S,
    4. Mulpur B, et al

    . Abstract WP44: less infarct volume growth in early window mechanical thrombectomy compared to late window in emergent large vessel occlusion. In: Proceedings of the International Stroke Conference, Los Angeles, California. February 18–21, 2020
13. 13.↵
    2. Ben Hassen W,
    3. Tordjman M,
    4. Boulouis G, et al

    . Benefit of first-pass complete reperfusion in thrombectomy is mediated by limited infarct growth. Eur J Neurol 2021;28:124–31 doi:10.1111/ene.14490 pmid:32896067

    CrossRefPubMed
14. 14.↵
    2. Federau C,
    3. Mlynash M,
    4. Christensen S, et al

    . Evolution of volume and signal intensity on fluid-attenuated inversion recovery MR images after endovascular stroke therapy. Radiology 2016;280:184–192 doi:10.1148/radiol.2015151586 pmid:26761721

    CrossRefPubMed
15. 15.↵
    2. Federau C,
    3. Christensen S,
    4. Mlynash M, et al

    . Comparison of stroke volume evolution on diffusion-weighted imaging and fluid-attenuated inversion recovery following endovascular thrombectomy. Int J Stroke 2017;12:510–18 doi:10.1177/1747493016677985 pmid:27811306

    CrossRefPubMed
16. 16.↵
    2. Gwak DS,
    3. Park HK,
    4. Jung C, et al

    . Infarct growth patterns may vary in acute stroke due to large vessel occlusion and recanalization with endovascular therapy. Eur Radiol 2020;30:6432–40 doi:10.1007/s00330-020-07068-1 pmid:32676782

    CrossRefPubMed
17. 17.↵
    2. Inoue M,
    3. Mlynash M,
    4. Christensen S, et al

    . Early diffusion-weighted imaging reversal after endovascular reperfusion is typically transient in patients imaged 3 to 6 hours after onset. Stroke 2014;45:1024–28 doi:10.1161/STROKEAHA.113.002135 pmid:24558095

    Abstract/FREE Full Text
18. 18.↵
    2. Regenhardt RW,
    3. Etherton MR,
    4. Das AS, et al

    . Infarct growth despite endovascular thrombectomy recanalization in large vessel occlusive stroke. J Neuroimaging 2021;31:15564 doi:10.1111/jon.12796] pmid:33119954

    CrossRefPubMed
19. 19.↵
    2. Schiphorst AT,
    3. Charron S,
    4. Hassen WB, et al

    . Tissue no-reflow despite full recanalization following thrombectomy for anterior circulation stroke with proximal occlusion: a clinical study. J Cereb Blood Flow Metab 2021;41:253–66 doi:10.1177/0271678X20954929 pmid:32960688

    CrossRefPubMed
20. 20.↵
    2. Yoo J,
    3. Choi JW,
    4. Lee SJ, et al

    . Ischemic diffusion lesion reversal after endovascular treatment. Stroke 2019;50:1504–09 doi:10.1161/STROKEAHA.118.024263 pmid:31043151

    CrossRefPubMed
21. 21.↵
    2. Boers AM,
    3. Jansen IG,
    4. Brown S, et al

    . Mediation of the relationship between endovascular therapy and functional outcome by follow-up infarct volume in patients with acute ischemic stroke. JAMA Neurol 2019;76:194–202 doi:10.1001/jamaneurol.2018.3661 pmid:30615038

    CrossRefPubMed
22. 22.↵
    2. Choi JH,
    3. Pile-Spellman J

    . Reperfusion changes after stroke and practical approaches for neuroprotection. Neuroimaging Clin N Am 2018;28:663–82 doi:10.1016/j.nic.2018.06.008 pmid:30322601

    CrossRefPubMed
23. 23.↵
    2. Khatri R,
    3. McKinney AM,
    4. Swenson B, et al

    . Blood-brain barrier, reperfusion injury, and hemorrhagic transformation in acute ischemic stroke. Neurology 2012;79:S52–57 doi:10.1212/WNL.0b013e3182697e70 pmid:23008413

    FREE Full Text
24. 24.↵
    2. Xu W,
    3. Zhang Y,
    4. Su J, et al

    . Ischemia reperfusion injury after gradual versus rapid flow restoration for middle cerebral artery occlusion rats. Sci Rep 2018;8:1638 doi:10.1038/s41598-018-20095-9 pmid:29374244

    CrossRefPubMed
25. 25.↵
    2. Sutherland BA,
    3. Neuhaus AA,
    4. Couch Y, et al

    . The transient intraluminal filament middle cerebral artery occlusion model as a model of endovascular thrombectomy in stroke. J Cereb Blood Flow Metab 2016;36:363–69 doi:10.1177/0271678X15606722 pmid:26661175

    CrossRefPubMed
26. 26.↵
    2. Pillai DR,
    3. Dittmar MS,
    4. Baldaranov D, et al

    . Cerebral ischemia-reperfusion injury in rats–a 3 T MRI study on biphasic blood-brain barrier opening and the dynamics of edema formation. J Cereb Blood Flow Metab 2009;29:1846–55 doi:10.1038/jcbfm.2009.106 pmid:19654585

    CrossRefPubMed
27. 27.↵
    2. Nour M,
    3. Scalzo F,
    4. Liebeskind DS

    . Ischemia-reperfusion injury in stroke. Interv Neurol 2012;1:185–99 doi:10.1159/000353125 pmid:25187778

    CrossRefPubMed
28. 28.↵
    2. Sah RG,
    3. d'Esterre CD,
    4. Hill MD, et al

    . Diffusion-weighted imaging lesion growth occurs despite recanalization in acute ischemic stroke: implications for future treatment trials. Int J Stroke 2019;14:257–64 doi:10.1177/1747493018798550 pmid:30179075

    CrossRefPubMed
29. 29.↵
    2. Tipirneni-Sajja A,
    3. Christensen S,
    4. Straka M, et al

    . Prediction of final infarct volume on subacute MRI by quantifying cerebral edema in ischemic stroke. J Cereb Blood Flow Metab 2017;37:3077–84 doi:10.1177/0271678X16683960 pmid:28155584

    CrossRefPubMed
30. 30.↵
    2. Harston GW,
    3. Carone D,
    4. Sheerin F, et al

    . Quantifying infarct growth and secondary injury volumes: comparing multimodal image registration measures. Stroke 2018;49:1647–55 doi:10.1161/STROKEAHA.118.020788 pmid:29895538

    Abstract/FREE Full Text
31. 31.↵
    2. Simard JM,
    3. Kent TA,
    4. Chen M, et al

    . Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol 2007;6:258–68 doi:10.1016/S1474-4422(07)70055-8 pmid:17303532

    CrossRefPubMedWeb of Science
32. 32.↵
    2. Broocks G,
    3. Flottmann F,
    4. Ernst M, et al

    . Computed tomography-based imaging of voxel-wise lesion water uptake in ischemic brain: relationship between density and direct volumetry. Invest Radiol 2018;53:207–13 doi:10.1097/RLI.0000000000000430 pmid:29200013

    CrossRefPubMed
33. 33.↵
    2. Broocks G,
    3. Faizy TD,
    4. Flottmann F, et al

    . Subacute infarct volume with edema correction in computed tomography is equivalent to final infarct volume after ischemic stroke: improving the comparability of infarct imaging endpoints in clinical trials. Invest Radiol 2018;53:472–76 doi:10.1097/RLI.0000000000000475 pmid:29668493

    CrossRefPubMed
34. 34.↵
    2. Broocks G,
    3. Hanning U,
    4. Faizy TD, et al

    . Ischemic lesion growth in acute stroke: water uptake quantification distinguishes between edema and tissue infarct. J Cereb Blood Flow Metab 2020;40:823–32 doi:10.1177/0271678X19848505 pmid:31072174

    CrossRefPubMed
35. 35.↵
    2. Kaesmacher J,
    3. Dobrocky T,
    4. Heldner MR, et al

    . Systematic review and meta-analysis on outcome differences among patients with TICI2b versus TICI3 reperfusions: success revisited. J Neurol Neurosurg Psychiatry 2018;89:910–17 doi:10.1136/jnnp-2017-317602 pmid:29519899

    Abstract/FREE Full Text
36. 36.↵
    2. Chamorro Á,
    3. Blasco J,
    4. López A, et al

    . Complete reperfusion is required for maximal benefits of mechanical thrombectomy in stroke patients. Sci Rep 2017;7:11636 doi:10.1038/s41598-017-11946-y pmid:28912596

    CrossRefPubMed
37. 37.↵
    2. Rangaraju S,
    3. Aghaebrahim A,
    4. Streib C, et al

    . Abstract T MP7: TICI 2B vs. TICI 3: differences in infarct volumes and clinical outcomes in proximal intracranial large vessel occlusions treated with endovascular therapy. In: Proceedings of the International Stroke Conference, Los Angeles, California. January 23–26, 2018
38. 38.↵
    2. Marto JP,
    3. Strambo D,
    4. Hajdu SD, et al

    . Twenty-four-hour reocclusion after successful mechanical thrombectomy: associated factors and long-term prognosis. Stroke 2019;50:2960–63 doi:10.1161/STROKEAHA.119.026228 pmid:31535931

    CrossRefPubMed
39. 39.↵
    2. Mosimann PJ,
    3. Kaesmacher J,
    4. Gautschi D, et al

    . Predictors of unexpected early reocclusion after successful mechanical thrombectomy in acute ischemic stroke patients. Stroke 2018;49:2643–51 doi:10.1161/STROKEAHA.118.021685 pmid:30355192

    CrossRefPubMed
40. 40.↵
    2. Santana D,
    3. Laredo C,
    4. Renú A, et al

    . Incidence and clinico-radiological correlations of early arterial reocclusion after successful thrombectomy in acute ischemic stroke. Transl Stroke Res 2020;11:1314–21 doi:10.1007/s12975-020-00816-x pmid:32314181

    CrossRefPubMed
41. 41.↵
    2. Almekhlafi MA,
    3. Modi J,
    4. Menon B, et al

    . Abstract 3232: distal embolization predicts infarct growth and futile recanalization after endovascular stroke therapy. In: Proceedings of the International Stroke Conference, New Orleans, Louisiana. February 1–3, 2012
42. 42.↵
    2. Kaesmacher J,
    3. Kurmann C,
    4. Jungi N, et al

    . Infarct in new territory after endovascular stroke treatment: a diffusion-weighted imaging study. Sci Rep 2020;10:8366 doi:10.1038/s41598-020-64495-2 pmid:32433478

    CrossRefPubMed
43. 43.↵
    2. Shuaib A,
    3. Butcher K,
    4. Mohammad AA, et al

    . Collateral blood vessels in acute ischaemic stroke: a potential therapeutic target. Lancet Neurol 2011;10:909–21 doi:10.1016/S1474-4422(11)70195-8 pmid:21939900

    CrossRefPubMedWeb of Science
44. 44.↵
    2. An JQ,
    3. Cheng YW,
    4. Guo YC, et al

    . Safety and efficacy of remote ischemic postconditioning after thrombolysis in patients with stroke. Neurology 2020;95:e3355–63 doi:10.1212/WNL.0000000000010884 pmid:33028663

    Abstract/FREE Full Text
45. 45.↵
    2. England TJ,
    3. Hedstrom A,
    4. O'Sullivan SE, et al

    . Remote ischemic conditioning after stroke trial 2: a Phase IIb randomized controlled trial in hyperacute stroke. J Am Heart Assoc 2019;8:e013572 doi:10.1161/JAHA.119.013572 pmid:31747864

    CrossRefPubMed
46. 46.↵
    2. Hill MD,
    3. Goyal M,
    4. Menon BK, et al

    . ESCAPE-NA1 Investigators. Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial. Lancet 2020;395:878–87 doi:10.1016/S0140-6736(20)30258-0 pmid:32087818

    CrossRefPubMed
47. 47.↵
    2. Chamorro A,
    3. Amaro S,
    4. Castellanos M, et al

    . URICO-ICTUS Investigators. Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial. Lancet Neurol 2014;13:453–60 doi:10.1016/S1474-4422(14)70054-7 pmid:24703208

    CrossRefPubMedWeb of Science
48. 48.↵
    2. Kuczynski AM,
    3. Demchuk AM,
    4. Almekhlafi MA

    . Therapeutic hypothermia: applications in adults with acute ischemic stroke. Brain Circ 2019;5:43–54 doi:10.4103/bc.bc_5_19 pmid:31334356

    CrossRefPubMed
49. 49.↵
    2. Wu C,
    3. Zhao W,
    4. An H, et al

    . Safety, feasibility, and potential efficacy of intraarterial selective cooling infusion for stroke patients treated with mechanical thrombectomy. J Cereb Blood Flow Metab 2018;38:2251–60 doi:10.1177/0271678X18790139 pmid:30019993

    CrossRefPubMed
50. 50.↵
    2. Chalela JA,
    3. Kidwell CS,
    4. Nentwich LM, et al

    . Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison. Lancet 2007;369:293–98 doi:10.1016/S0140-6736(07)60151-2 pmid:17258669

    CrossRefPubMedWeb of Science
51. 51.↵
    2. Baron JC,
    3. Yamauchi H,
    4. Fujioka M, et al

    . Selective neuronal loss in ischemic stroke and cerebrovascular disease. J Cereb Blood Flow Metab 2014;34:2–18 doi:10.1038/jcbfm.2013.188 pmid:24192635

    CrossRefPubMed
52. 52.↵
    2. Goyal M,
    3. Ospel JM,
    4. Menon B, et al

    . Challenging the ischemic core concept in acute ischemic stroke imaging. Stroke 2020;51:3147–55 doi:10.1161/STROKEAHA.120.030620 pmid:32933417

    CrossRefPubMed