Article Figures & Data
Figures
- Fig 1.
Schematic illustrating flow-limited contrast extravasation. Due to high permeability, the rate of leakage within the voxel depends on the amount of plasma reaching the voxel per unit of time (plasma flow). The venous blood would be “clean” of contrast.
- Fig 2.
Schematic illustrating 2 voxels with similar Ktrans values: the first one showing high permeability and low surface area and the second one with low permeability and high surface area.
- Fig 3.
Ktrans (A), CBV (B), and Vp (C) maps through the center of a grade IV glioma. The white line connects corresponding pixels for the correlation study.
- Fig 4.
Ktrans (A), CBV (B), and Vp (C) maps through the center of a grade IV glioma. The arrow points toward an area in the posterior aspect of the tumor showing high CBV and Vp values but only mildly elevated Ktrans values.
Tables
- Table 1:
Median, maximum, minimum, and interquartile range of nCBV, nVp, and Ktrans values
nCBV nVp Ktrans (min−1) Median 3.787 13.2 0.1841 Interquartile range 2.887–5.187 7.806–18.755 0.127–0.3125 Range 1.420–11.271 4.769–62.293 0.0471–0.987 Note:—nCBV indicates normalized CBV; nVp, normalized Vp.
- Table 2:
Results of the correlation study performed in a randomly selected sample of 40% (104,171 pixels)
CBV and Ktrans Vp and Ktrans Vp and CBV Spearman rank correlation coefficients 0.113 (P < .001) 0.256 (P < .001) 0.382 (P < .001)
