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Research ArticleBrain

Evaluation of Virtual Noncontrast Images Obtained from Dual-Energy CTA for Diagnosing Subarachnoid Hemorrhage

X.Y. Jiang, S.H. Zhang, Q.Z. Xie, Z.J. Yin, Q.Y. Liu, M.D. Zhao, X.L. Li and X.J. Mao
American Journal of Neuroradiology May 2015, 36 (5) 855-860; DOI: https://doi.org/10.3174/ajnr.A4223
X.Y. Jiang
aFrom the Departments of Radiology (X.Y.J., Z.J.Y., Q.Y.L., M.D.Z., X.L.L., X.J.M.)
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S.H. Zhang
cDepartment of Radiology (S.H.Z.), Shandong Cancer Hospital and Institute, Shandong, P.R. China.
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Q.Z. Xie
bPediatrics (Q.Z.X.), Affiliated Hospital of Binzhou Medical University, Shandong, P.R. China
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Z.J. Yin
aFrom the Departments of Radiology (X.Y.J., Z.J.Y., Q.Y.L., M.D.Z., X.L.L., X.J.M.)
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Q.Y. Liu
aFrom the Departments of Radiology (X.Y.J., Z.J.Y., Q.Y.L., M.D.Z., X.L.L., X.J.M.)
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M.D. Zhao
aFrom the Departments of Radiology (X.Y.J., Z.J.Y., Q.Y.L., M.D.Z., X.L.L., X.J.M.)
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X.L. Li
aFrom the Departments of Radiology (X.Y.J., Z.J.Y., Q.Y.L., M.D.Z., X.L.L., X.J.M.)
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X.J. Mao
aFrom the Departments of Radiology (X.Y.J., Z.J.Y., Q.Y.L., M.D.Z., X.L.L., X.J.M.)
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  • Fig 1.
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    Fig 1.

    A 71-year-old woman with SAH missed on VNC images. The onset time of SAH was 12 days prior. CTA shows an aneurysm of the left MCA. A and C, VNC image; B and D, TNC image; E, CTA image.

  • Fig 2.
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    Fig 2.

    A 78-year-old woman. The onset time of SAH was 17 hours prior. CTA shows an aneurysm in the right MCA. A, VNC image; B, TNC image; C, CTA image.

  • Fig 3.
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    Fig 3.

    A 58-year-old man. The onset time of SAH was 2.5 days prior. CTA and DSA show an aneurysm of the anterior communicating artery. Both VNC and TNC images find SAH, but the cortical sulci of right frontal lobe appears to have slightly higher attenuation on the VNC images than on TNC images. A, VNC image; B, TNC image; C, CTA image.

Tables

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    Table 1:

    Cases of SAH detected on TNC and VNC images at the individual level

    VNCTNCTotal
    PositiveNegative
    Positive52052
    Negative32932
    Total552984
    • View popup
    Table 2:

    Number of SAH lesions detected on TNC and VNC images at the lesion level

    VNCTNCTotal
    PositiveNegative
    Positive56250612
    Negative8615701656
    Total64816202268
    • View popup
    Table 3:

    Evaluation of VNC images for diagnosing SAH

    VNC ImagesSensitivity (%)Specificity (%)Positive Predictive Value (%)Negative Predictive Value (%)
    At the individual level94.510010090.6
    At the lesion level86.796.991.894.8
    • View popup
    Table 4:

    Radiation dose

    Dual-Energy CTATNC Brain CT
    HeadHead and Neck
    CTDIvol (mGy)9.06 ± 0.5210.43 ± 0.3855.71 ± 7.28
    DLP (mGy × cm)229.11 ± 41.50398.44 ± 21.71773.49 ± 104.06
    • Note:—CTDIvol indicates volume CT dose index; DLP, dose-length product.

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American Journal of Neuroradiology: 36 (5)
American Journal of Neuroradiology
Vol. 36, Issue 5
1 May 2015
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Cite this article
X.Y. Jiang, S.H. Zhang, Q.Z. Xie, Z.J. Yin, Q.Y. Liu, M.D. Zhao, X.L. Li, X.J. Mao
Evaluation of Virtual Noncontrast Images Obtained from Dual-Energy CTA for Diagnosing Subarachnoid Hemorrhage
American Journal of Neuroradiology May 2015, 36 (5) 855-860; DOI: 10.3174/ajnr.A4223

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Evaluation of Virtual Noncontrast Images Obtained from Dual-Energy CTA for Diagnosing Subarachnoid Hemorrhage
X.Y. Jiang, S.H. Zhang, Q.Z. Xie, Z.J. Yin, Q.Y. Liu, M.D. Zhao, X.L. Li, X.J. Mao
American Journal of Neuroradiology May 2015, 36 (5) 855-860; DOI: 10.3174/ajnr.A4223
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  • Detection of Early Ischemic Changes with Virtual Noncontrast Dual-Energy CT in Acute Ischemic Stroke: A Noninferiority Analysis
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